• Common side effects of montelukast include upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection. The Major Antihistamine Effects of Diphenhydramine Prevents Histamine-Mediated: constriction of respiratory smooth muscle. rapid vasodilation in blood vessels. increased capillary permeability and subsequent edema. sensations of itching, pain, and “flare” formation. increase in heart rate and strength of contraction.Higher dosage or long-term use of common drugs with anticholinergic effects is linked to significantly increased risk of dementia - including Alzheimer’s - says large study.Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This article is for information only. DO NOT use it to treat or manage an actual overdose. Long-term use of Benadryl can also lead to constipation and confusion. Interactions. Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine. Answer (1 of 2): Here is one long term study: “These drugs are called anticholinergics, among them the first-generation antihistamines that are now marketed as sleep aids.Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache.Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. Hives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ...Yes, certain side effects are possible after using Benadryl long term. For example, long-term use of Benadryl may cause: an increased risk of dementia; withdrawal symptoms after the drug is stopped* However, keep in mind that doctors typically don’t recommend taking Benadryl as a long-term treatment.Take one to two 50mg tablets at least 30 minutes prior to bedtime. The maximum dose of two tablets works best for sleep. You can take Dramamine with or without food, but make sure you take a dose with a full glass of water 1 2. Swallow tablets whole; don't crush or chew. Plan on taking Dramamine four to six hours prior to waking for the next ...Yes, certain side effects may be possible with long-term use of Benadryl. However, doctors usually don’t recommend Benadryl for long-term use. Instead, they typically advise short-term use of the drug to ease certain symptoms. The drug’s label information* for Benadryl does not specify any long-term side effects for this drug.Apr 9, 2020 · Diphenhydramine, brand name Benadryl ®, is one of the oldest and most frequently used over-the-counter medications for children. However, many better options are now widely available, all of which are faster acting, longer lasting, with less side effects. Antihistamines counteract the effect of histamine throughout the body, and treat a range ... and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increased The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ...Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...Benadryl dosage for dogs. The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to ...Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...May 25, 2023 · Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Not able to pass urine or change in how much urine is passed. A very bad skin reaction ( Stevens-Johnson syndrome / toxic epidermal necrolysis) may happen. May 13, 2021 · The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ... While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https ...Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago.Aug 25, 2021 · Examples of Viagra’s more commonly reported side effects include: headache. flushing (temporary warmth, redness, or deepening of skin color) stuffy nose. indigestion (upset stomach) mild vision ... Long-Term Side Effects of Diphenhydramine Abuse. Continued diphenhydramine use can cause long-term adverse side effects that result in permanent damage. Not only will prolonged use cause harm, but it can lead to other aspects such as dependence on the medication. Common long-term side effects of prolonged diphenhydramine use include: Dependence. Yeah, look at r/dph.Datura is even worse. It's like dph, but way more likely to kill you or make you go blind. Shadow people and spiders and having full conversations with people who don't exist usually only happens in the 400+ category. Between 150mg and there, it's usually just having to piss but being unable to, dysphoria/fear, beWhat are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ...What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ...Pay attention to the side effects of Benadryl, especially if you’re an older adult. The body responds differently to Benadryl as you get older. And you may develop side effects that were never a problem before. Benadryl is not intended to be used as a daily, long-term medication for sleep or other issues.Jun 14, 2023 · The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ... Dear Alice, I've experimented with the abuse of Benadryl on a few occasions now and have been absolutely blown off to another world, I was just curious as to what the side affects, long or short-term, can look like, and what the dangers are of abusing this drug (acetaminophen free).Nov 14, 2022 · A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ... Take one to two 50mg tablets at least 30 minutes prior to bedtime. The maximum dose of two tablets works best for sleep. You can take Dramamine with or without food, but make sure you take a dose with a full glass of water 1 2. Swallow tablets whole; don't crush or chew. Plan on taking Dramamine four to six hours prior to waking for the next ...Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose. Warnings What to ask your doctor Q&A Benadryl (diphenhydramine) is used for allergies and allergic reactions, as well as common cold symptoms. Benadryl can cause mild or serious side...Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom).May 19, 2022 · Yes, certain side effects are possible after using Benadryl long term. For example, long-term use of Benadryl may cause: an increased risk of dementia; withdrawal symptoms after the drug is stopped* However, keep in mind that doctors typically don’t recommend taking Benadryl as a long-term treatment. Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect. 5. Tips. Benadryl may be taken with or without food. Take exactly as directed.Apr 23, 2021 · Hives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ... Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory.Apr 8, 2023 · The main long-term side effects of Plaquenil are eye-related. ... To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine ... Apr 23, 2021 · Hives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ... Benadryl dosage for dogs. The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to ...• Common side effects of montelukast include upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection. Oct 6, 2015 · Caution should be exercised for long-term use of Benadryl (diphenhydramine), an antihistamine and a non-benzodiazepine sedative-hypnotic, because of the association of increased risk for dementia. Jun 8, 2022 · Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom). Apr 6, 2023 · Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https ... Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago.Official answer. Diphenhydramine can be used as a short-term sleep aid to help ease occasional sleep problems. Older adults, children under age 16 and pregnant women should avoid taking diphenhydramine, as the risks to these groups may outweigh the benefits. Diphenhydramine should not be taken as a treatment for chronic insomnia. Benadryl can cause some children to be hyperactive. OTC cough and cold medicine should not be given to children under the age of 4. Research has shown that these products do not work in children younger than 6 years old and can have serious side effects.Aug 1, 2023 · skin rash. swollen joints. stomach discomfort, upset or pain. tender swollen glands in neck. tremor. unusual excitement, nervousness, restlessness, or irritability. vomiting. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Apr 8, 2023 · The main long-term side effects of Plaquenil are eye-related. ... To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine ... The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ...People who take too much Benadryl start to experience many of the medication’s side effects. These can include mild symptoms, such as dry mouth, constipation, and tiredness. Usually, the more Benadryl a person takes, the worse these side effects become. In more severe Benadryl overdose cases, symptoms like seizures, irregular heartbeats, and ...Apr 11, 2018 · Benadryl is a first-generation antihistamine, meaning it is one of the earlier drugs developed in this category of medications. First-generation antihistamines, like Benadryl, are often noted for their sedative side effects as they have the ability to travel to your brain (i.e. crosses the blood-brain barrier), which is why they can make you ... Uses Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough,...The Major Antihistamine Effects of Diphenhydramine Prevents Histamine-Mediated: constriction of respiratory smooth muscle. rapid vasodilation in blood vessels. increased capillary permeability and subsequent edema. sensations of itching, pain, and “flare” formation. increase in heart rate and strength of contraction.Jan 24, 2018 · Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory. Long-term use of Benadryl can also lead to constipation and confusion. Interactions. Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine.Inhaled corticosteroids are often used daily as part of treatment for asthma caused or complicated by reactions to airborne allergy triggers (allergens). Side effects are generally minor and can include mouth and throat irritation and oral yeast infections. Some inhalers combine corticosteroids with long-acting bronchodilators.Oct 9, 2018 · Many older adults may take sleeping pills because pain, nerve problems or other health issues are keeping them up at night, she says. For these people, a sleeping pill is standing in the way of ... Benadryl dosage for dogs. The correct dosage of diphenhydramine for dogs depends on their weight. A small dog will need much less than a big dog to receive the same positive effects. According to ...One Benadryl per night seems to be enough to keep the ears dry & the resulting nausea at bay. I must admit that I'm not sure this is still even a problem for me. The last time I stopped to see if I still needed it was about 2 years ago. After 3 days, the dizziness/nausea/inner ear issues came back, so I promptly started taking the nightly ...It can sometimes cause a decrease in memory, confusion, and thinking issues. These side effects are more common in elders. In addition, taking Benadryl long-term might increase the risk of dementia. People aged> 65 who took medications such as Benadryl daily for over three years had an increased risk of dementia.Nov 15, 2017 · Asthma. Car Sickness. Insomnia. Motion sickness. Reactions to Vaccines. Because one of the common side effect of Benadryl in dogs is drowsiness, your vet may use it to alleviate dog anxiety, particularly associated with traveling and motion sickness that may occur during plane rides or car trips. Impaired concentration. Memory difficulties. Anxiety. Stomach disturbances. Nausea and vomiting. A dry mouth. Constipation. Liver problems, etc. In certain people, a paradoxical reaction to diphenhydramine is possible, meaning that the drug causes different symptoms than the intended ones.Nov 14, 2022 · A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ... When corrected based on the number of drugs with anticholinergic effects an individual was taking, the odds ratio for cognitive impairment was 1.46 with a p value of .0181. However, overall the authors conclude that their data did not support the hypothesis that the use of anticholinergic medications increased the risk of alzheimer’s dementia ...Nov 15, 2019 · Central side effects. Since these actions are disrupted by sedating antihistamines, these drugs produce sedation, drowsiness, tiredness, lack of concentration, difficulty in learning and memory ... Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...Giving Benadryl to dogs long term in some cases can be helpful for the dog. However, one of the main side effects of Benadryl is drowsiness. Giving too much dog Benadryl can cause the dog to go into a deep sleep for some time. Additionally, in some cases Benadryl can cause upset stomach and even possibly loss of appetite.Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose.Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating. General The most commonly reported side effects included somnolence, dizziness, and incoordination.May 7, 2021 · There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria) A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ...Benadryl Addiction Side Effects. Despite having numerous benefits in the medical world, Benadryl has its share of negative side effects when abused. Some effects are short term whereas others can last a lifetime. A user can either encounter psychological effects, physical effects, or both. Some of the physical effects to watch out for include ...Long-Term Side Effects of Diphenhydramine Abuse. Continued diphenhydramine use can cause long-term adverse side effects that result in permanent damage. Not only will prolonged use cause harm, but it can lead to other aspects such as dependence on the medication. Common long-term side effects of prolonged diphenhydramine use include: Dependence. January 19, 2022. By Harvard Health Publishing Staff. A report published in JAMA Internal Medicine several years ago highlighted a link between long-term use of anticholinergic medications like Benadryl and dementia. While this study and other observational studies have also found this association, it doesn't prove that these drugs cause dementia.Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose. Answer (1 of 2): Here is one long term study: “These drugs are called anticholinergics, among them the first-generation antihistamines that are now marketed as sleep aids.Apr 6, 2023 · Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https ... Examples of Viagra’s more commonly reported side effects include: headache. flushing (temporary warmth, redness, or deepening of skin color) stuffy nose. indigestion (upset stomach) mild vision ...Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ...The short answer seems to be yes. While occasionally taking a Benadryl for sleep probably won’t lead to significant weight gain, chronic use of antihistamines can interfere with weight loss efforts. If you need an antihistamine for frequent allergy symptoms, however, the best choice is Claritin because it does not cross into the brain and has ...Side Effects Of Benadryl. Overall, Benadryl is well tolerated and side effects are generally mild in severity. If they do occur, they should subside 4 to 6 hours after dosing, although this can be extended in those with kidney disease and in the elderly. Below, we discuss the most common side effects associated with Benadryl.Children's Benadryl Allergy - Uses, Side Effects, and More Generic Name(S): diphenhydramine HCl, diphenhydramine citrate ... (such as long-acting tablets/capsules) are not recommended for use in ...
Central side effects. Since these actions are disrupted by sedating antihistamines, these drugs produce sedation, drowsiness, tiredness, lack of concentration, difficulty in learning and memory .... 0z
There could be both short- and long-term consequences. Worried about the side effects of Ambien, Lunesta or other sleep aids? ... Diphenhydramine is an anticholinergic drug, which means it blocks ...Pay attention to the side effects of Benadryl, especially if you’re an older adult. The body responds differently to Benadryl as you get older. And you may develop side effects that were never a problem before. Benadryl is not intended to be used as a daily, long-term medication for sleep or other issues.May 7, 2021 · There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria) Jul 31, 2023 · Extrapyramidal side effects (EPS), commonly referred to as drug-induced movement disorders are among the most common adverse drug effects patients experience from dopamine-receptor blocking agents. It was first described in 1952 after chlorpromazine-induced symptoms resembling Parkinson disease.[1] A variety of movement phenotypes has since been described along the EPS spectrum, including ... Apr 11, 2018 · Benadryl is a first-generation antihistamine, meaning it is one of the earlier drugs developed in this category of medications. First-generation antihistamines, like Benadryl, are often noted for their sedative side effects as they have the ability to travel to your brain (i.e. crosses the blood-brain barrier), which is why they can make you ... Aug 23, 2021 · Symptoms can be mild or serious and can include: skin rash. itchiness. flushing (temporary warmth, redness, or deepening of skin color) swelling under your skin, typically in your eyelids, lips, hands, or feet. swelling of your mouth, tongue, or throat, which can make it hard to breathe. Diphenhydramine is contraindicated in premature infants and neonates, as well as people who are breastfeeding. It is a pregnancy Category B drug. Diphenhydramine has additive effects with alcohol and other CNS depressants. Monoamine oxidase inhibitors prolong and intensify the anticholinergic effect of antihistamines. OverdoseDiphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago.Jun 14, 2023 · The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ... Dec 1, 2022 · Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ... While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:What are the side effects of Benadryl ... Diphenhydramine is only for short-term use until your symptoms clear up. ... (such as a long car ride, airplane or boat travel, amusement park rides, etc ...Diphenhydramine, which is the active ingredient in ZzzQuil, can cause side effects in some people. The most common side effects of diphenhydramine include: drowsiness. dizziness. loss of ...• Common side effects of montelukast include upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection. “The antihistamine diphenhydramine is only approved for management of short-term or temporary sleep difficulties, particularly in those people who have problems falling asleep,” Dr. What are the negative effects of Benadryl? Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of ...People who take too much Benadryl start to experience many of the medication’s side effects. These can include mild symptoms, such as dry mouth, constipation, and tiredness. Usually, the more Benadryl a person takes, the worse these side effects become. In more severe Benadryl overdose cases, symptoms like seizures, irregular heartbeats, and ...Anxiety. Asthma. Car Sickness. Insomnia. Motion sickness. Reactions to Vaccines. Because one of the common side effect of Benadryl in dogs is drowsiness, your vet may use it to alleviate dog anxiety, particularly associated with traveling and motion sickness that may occur during plane rides or car trips.While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:Oct 6, 2015 · Caution should be exercised for long-term use of Benadryl (diphenhydramine), an antihistamine and a non-benzodiazepine sedative-hypnotic, because of the association of increased risk for dementia. .